| Season | Date | Home Team | Score | Away Team | Pts Diff |
|---|---|---|---|---|---|
| 24 | 04-05-2024 | Leeds | 1 - 2 | Southampton | 0 |
| 24 | 27-04-2024 | Southampton | 0 - 1 | Stoke | -3 |
| 24 | 23-04-2024 | Leicester | 5 - 0 | Southampton | -1 |
| 24 | 20-04-2024 | Cardiff | 2 - 1 | Southampton | -3 |
| 24 | 16-04-2024 | Southampton | 3 - 0 | Preston | 3 |
| 24 | 13-04-2024 | Southampton | 3 - 2 | Watford | 0 |
| 24 | 09-04-2024 | Southampton | 2 - 1 | Coventry | 2 |
| 24 | 06-04-2024 | Blackburn | 0 - 0 | Southampton | 0 |
| 24 | 01-04-2024 | Ipswich | 3 - 2 | Southampton | -3 |
| 24 | 29-03-2024 | Southampton | 1 - 1 | Middlesbrough | -2 |
| 24 | 09-03-2024 | Southampton | 4 - 2 | Sunderland | 2 |
| 24 | 02-03-2024 | Birmingham | 3 - 4 | Southampton | 0 |
| 24 | 24-02-2024 | Southampton | 1 - 2 | Millwall | -1 |
| 24 | 20-02-2024 | Southampton | 1 - 2 | Hull | -1 |
| 24 | 16-02-2024 | West Brom | 0 - 2 | Southampton | 2 |
| 24 | 13-02-2024 | Bristol City | 3 - 1 | Southampton | 0 |
| 24 | 10-02-2024 | Southampton | 5 - 3 | Huddersfield | 2 |
| 24 | 03-02-2024 | Rotherham | 0 - 2 | Southampton | 0 |
| 24 | 20-01-2024 | Swansea | 1 - 3 | Southampton | 0 |
| 24 | 13-01-2024 | Southampton | 4 - 0 | Sheffield Weds | 3 |
| 24 | 01-01-2024 | Norwich | 1 - 1 | Southampton | -2 |
| 24 | 29-12-2023 | Southampton | 2 - 1 | Plymouth | 2 |
| 24 | 26-12-2023 | Southampton | 5 - 0 | Swansea | 0 |
| 24 | 23-12-2023 | QPR | 0 - 1 | Southampton | 0 |
| 24 | 16-12-2023 | Southampton | 4 - 0 | Blackburn | 0 |
| 24 | 13-12-2023 | Coventry | 1 - 1 | Southampton | 0 |
| 24 | 09-12-2023 | Watford | 1 - 1 | Southampton | 1 |
| 24 | 02-12-2023 | Southampton | 2 - 0 | Cardiff | 0 |
| 24 | 29-11-2023 | Southampton | 1 - 0 | Bristol City | 0 |
| 24 | 25-11-2023 | Huddersfield | 1 - 1 | Southampton | -2 |
| 24 | 11-11-2023 | Southampton | 2 - 1 | West Brom | 3 |
| 24 | 04-11-2023 | Millwall | 0 - 1 | Southampton | 2 |
| 24 | 28-10-2023 | Southampton | 3 - 1 | Birmingham | 2 |
| 24 | 25-10-2023 | Preston | 2 - 2 | Southampton | 0 |
| 24 | 21-10-2023 | Hull | 1 - 2 | Southampton | 0 |
| 24 | 07-10-2023 | Southampton | 1 - 1 | Rotherham | 0 |
| 24 | 03-10-2023 | Stoke | 0 - 1 | Southampton | 3 |
| 24 | 30-09-2023 | Southampton | 3 - 1 | Leeds | 2 |
| 24 | 23-09-2023 | Middlesbrough | 2 - 1 | Southampton | 0 |
| 24 | 19-09-2023 | Southampton | 0 - 1 | Ipswich | -3 |
| 24 | 15-09-2023 | Southampton | 1 - 4 | Leicester | 0 |
| 24 | 02-09-2023 | Sunderland | 5 - 0 | Southampton | -1 |
| 24 | 26-08-2023 | Southampton | 2 - 1 | QPR | 0 |
| 24 | 19-08-2023 | Plymouth | 1 - 2 | Southampton | 2 |
| 24 | 12-08-2023 | Southampton | 4 - 4 | Norwich | -2 |
| 24 | 04-08-2023 | Sheffield Weds | 1 - 2 | Southampton | 0 |